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  王富

  博士，长聘副教授、博士生导师。2006年于内蒙古大学取得理学学士，2011年获得中科院理化技术研究所理学博士，2010-2011年获得中德联合培养项目，于德国马普高分子所学习，合作导师Prof. Dr. Wolfgang Knoll。获得中科院院长优秀奖学金、中科院优秀毕业生等荣誉。2011-2014年分别在德国马普生物物理化学研究所，合作导师Prof. Dr. Stefan W. Hell (2014年诺贝尔化学奖得主)、德国弗莱堡大学，合作导师Prof. Dr. Bernd Fakler研究组从事博士后研究工作。荣获第十一批国家青年特聘专家，在Advanced Materials, Advanced Functional Materials, ACS Nano等期刊发表论文六十多篇，授权发明专利十多项。主持国家自然科学基金项目、基金委重大科研装备研制课题、科技部重点研发项目课题、中科院科研装备研制等项目。担任中国生物医学工程学会生物医学光子学分会委员，中国光学学会生物医学光子学分会常委；任中国激光杂志社、BMEMat、JIOHS等期刊青年编委。

1. 超分辨荧光与光谱成像

2. 多模态光学诊疗

1.“双光子-受激发射损耗（STED）复合显微镜”，科技部重点研发专项 “数字诊疗装备研发”，课题负责人，441万。

2. “基于单一激光器的可调双色及双光子超分辨显微镜”，中科院科研装备研制项目，项目负责人，180万。

3.“实时原位超分辨光学成像关键问题研究”, 科技部重点研发专项“工程科学与综合交叉”，子课题负责人，76万。

4. “基于功能纳米材料的食品中农兽药残留物脱除技术研究”, 科技部重点研发专项 “食品安全关键技术研发”，子课题负责人，60万。

  5.  国家自然科学基金委重大科研仪器研制项目,课题负责人，150万。

近五年代表性论文：

(1)  Gao, B.; Gao, L.; Wang, J.; Huang, X.; Ge, W.; Li, S.; Wang, F. NIR-II Light Field Microscopy for Through-Skull Hemodynamic Volumetric Imaging in Awake Mice. Laser & Photonics Reviews 2025, 2401685.

(2)  Ge, W.; Huang, S.; Huang, X.; Gao, B.; Shen, Z.; Zhuang, X.; Wang, F. Synchronous Passivation Boosts the NIR-II Luminescence Efficiency of Ag₂S Nanocrystals for Effective Deep Tissue Lymphatic Mapping. ACS Nano 2025, 19 (6), 6601–6612.

(3)  Li, S.; Ge, W.; Huang, X.; Du, H.; Wang, F. Synergistic Intramolecular Charge Transfer Promotes Au Nanoclusters with Enhanced NIR-II Photoluminescence. J. Phys. Chem. Lett. 2025, 16 (5), 1221–1228.

( 4) Huang, X.; Yang, F.; Gao, B,; Ge, W.; Gao, L.; Wu, J.; Tu, S.; Wang, F. Free Carrier-Enhanced Bi/Bi₂S₃ Nanoparticles Enable Precise OCT Catheter-Guided Interventional Photothermal Therapy for Colorectal Cancer. Acta Biomaterialia. 2025.

(5)  Huang, X.; Ge, W.; Li, S.; Huang, R.; Wang, F. Transferrin-Based Bismuth Nanoparticles for Radiotherapy with Immunomodulation Against Orthotopic Glioma. Advanced Healthcare Materials 2025, 14 (7), 2404144.

(6)  Huang, X.; Gao, L,; Ge, W.; Li, S.; Liu, Y.; Fan, X.; Tu, S.; Wang, F. An Ultrasound-Activated Piezoelectric Sonosensitizer Enhances Mitochondrial Depolarization for Effective Treatment of Orthotopic Glioma. Acta Biomaterialia 2024, 190, 435–446.

(7)  Gao, L.; Gao, B.; Ge, W.; Li, S.; Wang, F. Stimulated Emission Depletion Imaging Reveals Mitochondrial Phenotypic Heterogeneity under Apoptosis Stimuli across Living Glioma Models. Nano Lett. 2024, 24 (49), 15904–15911.

(8) Gao, L.; Dalapati, R.; Gao, B.; Huang, X.; Zhao, D.; Wang, F.; Zang, L. Mitochondrial STED Imaging and Membrane Potential Monitoring with a Cationic Molecular Probe. Small Methods 2024, 8 (12), 2400525.

(9)  Ge, W.; Chen, G.; Huang, X.; Gao, B.; Wang, F. Heteroions Radii Matching Produced Intensely Luminescent Bismuth-Ag₂S Nanocrystals for through-Skull NIR-II Imaging of Orthotopic Glioma. Nano Lett. 2024, 24 (15), 4562–4570.

(10) Zhao, D.; Gao, L.; Huang, X.; Chen, G.; Gao, B.; Wang, J.; Gu, M.; Wang, F. Complementary Imaging of Nanoclusters Interacting with Mitochondria via Stimulated Emission Depletion and Scanning Transmission Electron Microscopy. Journal of Hazardous Materials 2024, 465, 133371.

(11) Zhao, D.; Huang, X.; Tian, Y.; Zou, J.; Wang, F.; Chen, X. Fluorescence Imaging-Incorporated Transcriptome Study of Glutathione Depletion-Enhanced Ferroptosis Therapy via Targeting Gold Nanoclusters. ACS Appl. Mater. Interfaces 2023，15, 5, 6385–6396.

(12) Huang, X.; Zha, F.; Zou, J.; Li, Y.; Wang, F.; Chen, X. Photoacoustic Imaging-Guided Synergistic Photothermal/Radiotherapy Using Plasmonic Bi/Bi₂O_3−x Nanoparticles. Advanced Functional Materials, 2022，2113353.

(13) Tian, Y.; Zhao, D.; Huang, X.; Guan, X.; Wang, F.; Wei, X. Extended π-Conjugative Carbon Nitride for Single 1064 nm Laser-Activated Photodynamic/Photothermal Synergistic Therapy and Photoacoustic Imaging. ACS Appl. Mater. Interfaces 2022, 14 (6), 7626–7635.

(14) Huang, X.; Zhang, W.; Peng, Y.; Gao, L.; Wang, F.; Wang, L.; Wei, X. A Multifunctional Layered Nickel Silicate Nanogenerator of Synchronous Oxygen Self-Supply and Superoxide Radical Generation for Hypoxic Tumor Therapy. ACS Nano 2022, 16 (1), 974–983.

(15) Peng, Y.; Huang, X.; Wang, F. Near-Infrared Emitting Gold–Silver Nanoclusters with Large Stokes Shifts for Two-Photon in Vivo Imaging. Chem. Commun. 2021, 57 (96), 13012–13015.